Endocrine Abstracts

The T2-weighted characteristics of GH-secreting pituitary adenomas have recently received particular attention from the research community. It now appears that somatotropinomas can be divided into groups with different behavior according to their T2-weighted signal. T2-hypointense adenomas are generally smaller, invade the cavernous sinus less frequently and are responsible for higher levels of GH-hypersecretion (Fig. 1). Treatment with somatostatin analogues, both before and ...

Introduction: Clinical research studies over the last 15 years have reported a significant burden of hypopituitarism in survivors of traumatic brain injury (TBI). However, these endocrine anomalies remain underdiagnosed.Patients and methods: We are studying data from a series of 75 TBI patients. They had a basal hormonal test, and dynamic confirmation tests if necessary. Somatotropic deficiency was defined by growth hormone (GH) remaining under 3 μg...

Introduction: Intracranial germ-cell tumors (GCT) are rare, occurring in less than 4% of pediatric patients. Histologically, they are divided into several types, among which germinomatous GCTs represent over 50% of cases. Depending on their location, GCTs usually present with symptoms of intracranial hypertension for pineal lesions, whereas suprasellar ones lead to visual disturbances or pituitary hormonal defects.We present the case of a bifocal intracr...